Achmatowicz pyranone reaction

What is Achmatowicz pyranone reaction?

The Achmatowicz pyranone reaction is a chemical process that involves creating pyran-3-ones from furfuryl alcohols. To begin, the alcohols are transformed into dialkoxydihydrofurans through techniques such as Clauson-Kaas electrochemical oxidation. The resulting compound is then subjected to acid hydrolysis.

Achmatowicz pyranone reaction
Achmatowicz pyranone reaction

Additionally, a variation of this reaction exists that produces an aza-analogue using furylacetamides.

 

References

  • O. Achmatowicz, jr.; P. Bukowski; B. Szechner; Z. Zwierzchowska; A. Zamojski, Tetrahedron, 1971, 27, 1973.
  • O. Achmatowicz, jr.; B. Szechner, Carbohydr. Res., 1976, 50, 23.
  • G. Grynkiewicz; O. Achmatowicz, jr.; H. Barton, Rocz. Ann. Soc. Chim. Pol., 1977, 51, 1663.
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