Alkylimino-de-oxo-bisubstitution

What is alkylimino-de-oxo-bisubstitution?

The process known as alkylimino-de-oxo-bisubstitution involves the reaction of carbonyl compounds and amines resulting in the formation of imines. This name is derived from the IUPAC Nomenclature for Transformations. The reaction necessitates an acid catalyst and is categorized as a nucleophilic addition wherein the amine adds to the carbonyl compound. This is followed by the transfer of a proton from nitrogen to oxygen which leads to the creation of a hemiaminal or carbinolamine, which is stable.

Alkylimino-de-oxo-bisubstitution - imine formation from cyclohexylamine and acetaldehyde -water is removed by Na<sub>2</sub>SO<sub>4</sub>
Alkylimino-de-oxo-bisubstitution (imine formation from cyclohexylamine and acetaldehyde. Water is removed by Na2SO4)

When primary amines are involved, water is eliminated in an elimination reaction resulting in the formation of an imine. When aryl amines are utilized, particularly stable Schiff bases are generated.

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