Baker-Ollis sydnones synthesis

What is Baker-Ollis sydnones synthesis?

The Baker-Ollis sydnones synthesis involves a straightforward process that utilizes specific dehydrating agents like acetic anhydride to produce sydnones.

Baker-Ollis sydnones synthesis
Baker-Ollis sydnones synthesis

Sydnones possess both biological and structural significance and were first identified by Earl and Wackney in 1935, but it wasn’t until 1946 that they were studied in detail. The unique chemical and physical properties of sydnones cannot be fully explained by a single valence structure, and various structures have been suggested to resolve this issue. The structure most commonly employed is the one presented by Baker and Ollis in 1957.

Sydnones represent just one out of approximately 288 potential five-membered ring systems that share comparable electronic characteristics, and only a limited number of these have been created thus far.

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