Bernthsen acridine synthesis

What is Bernthsen acridine synthesis?

The Bernthsen acridine synthesis is a method used to produce 5-substituted acridines. This process involves heating diarylamines in the presence of organic acids or anhydrides, typically with the addition of zinc chloride, ZnCl2.

Bernthsen acridine synthesis - general reaction scheme
Bernthsen acridine synthesis

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