Bischler-Möhlau indole synthesis

What is Bischler-Möhlau indole synthesis?

The Bischler-Möhlau indole synthesis is a chemical process that involves the formation of 2-substituted indoles by heating ω-halogeno- or ω-hydroxy-ketones with an excess of aniline.

Bischler-Möhlau indole synthesis
Bischler-Möhlau indole synthesis

The Bischler-Möhlau indole synthesis leads to the cyclization of the intermediate 2-arylaminoketone to form the desired 2-substituted indole product.

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