Bosch-Meiser urea synthesis

What is Bosch-Meiser urea synthesis?

The Bosch-Meiser urea synthesis is an industrial process that involves the reaction of carbon dioxide (CO2) with ammonia (NH3) to produce ammonium carbamate [NH4]โŠ•[H2NCO2]โŠ–. This intermediate is subsequently converted into urea.

Bosch-Meiser urea synthesis - general reaction scheme - ammonium carbamate [NH4]โŠ•[H2NCO2]โŠ– carbon dioxide ammonia CO2 NH3
Bosch-Meiser urea synthesis

The Bosch-Meiser urea synthesis is highly efficient and produces high yields of urea. It is also a relatively cost-effective method for producing urea compared to other methods such as the Haber-Bosch process. The process is widely used in the chemical industry, with many large-scale urea production plants using the Bosch-Meiser process..

However, the Bosch-Meiser urea synthesis does have some drawbacks. The high pressure and temperature required for the reaction make it an energy-intensive process.


C. Bosch and W. Meiser, โ€œProcess of manufacturing ureaโ€ U.S. Patent US 1429483 (1922)