Chretien-Longi reaction

What is Chretien-Longi reaction?

The Chretien-Longi reaction, which was initially discovered by Chretien and Longi in 1945, is a method of creating nitrite esters by treating alcohols with nitrous acid in an acidic aqueous solution. In the original procedure, sodium nitrite (NaNO2) was combined with the alcohol and then aluminum sulfate Al2(SO4)3 was added, leading to a decrease in pH. This reaction has been adapted to take place in acetic acid CH3COOH.

Chretien-Longi reaction
Chretien-Longi reaction

References

Chretien, A. and Longi, Y., Compd. Rent., 1945, 220, 746

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