García-González reaction

What is García-González reaction?

The García-González reaction is a chemical reaction discovered in the 1950s that involves the Knoevenagel condensation of unprotected sugars, using zinc chloride, ZnCl2 as a promoter. This method, also known as the García-González reaction, was largely forgotten for several decades until the emergence of new water-tolerant catalysts with Lewis acid behavior.

García-Gonzalez synthesis
García-Gonzalez synthesis

References

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