Gattermann-Skita synthesis

What is Gattermann-Skita synthesis?

The Gattermann-Skita synthesis is a method of organic synthesis used to produce pyridines. This process involves combining a malonic ester salt with dichloromethylamine CHNH2Cl2 in the presence of a base.

Gattermann–Skita synthesis - general reaction scheme
Gattermann-Skita synthesis

References

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