Pfau-Plattner azulene synthesis

What is Pfau-Plattner azulene synthesis?

The Pfau-Plattner azulene synthesis involves the formation of azulenes by expanding the ring size of indanes through the addition of diazoacetic ester, followed by hydrolysis, dehydrogenation, and decarboxylation of the resulting acid.

Plattner azulene synthesis

References

  • St. Pfau, A. and Plattner, P.A. (1939), Zur Kenntnis der flüchtigen Pflanzenstoffe VIII. Synthese des Vetivazulens. [On the knowledge of volatile plant substances VIII. synthesis of vetivazulen.] Helvetica Chimica Acta, 22: 202-208. https://doi.org/10.1002/hlca.19390220126
  • Plattner, P.A. and Wyss, J. (1940), Zur Kenntnis der Sesquiterpene. (45. Mitteilung). Synthese des 1,4-Dimethyl-azulens. [On the knowledge of the sesquiterpenes. (45th Announcement). Synthesis of 1,4-dimethyl azulene.] Helvetica Chimica Acta, 23: 907-911. https://doi.org/10.1002/hlca.194002301116
  • Plattner, P.A. and Wyss, J. (1941), Zur Kenntnis der Sesquiterpene;. (47. Mitteilung). Synthese einiger Mono- und Dimethyl-azulene. [On the knowledge of the sesquiterpenes;. (47th Communication). Synthesis of some mono- and dimethyl-azulenes.] Helvetica Chimica Acta, 24: 483-492. https://doi.org/10.1002/hlca.19410240166
  • Plattner, P.A. and Roniger, H. (1942), Zur Kenntnis der Sesquiterpene. (53. Mitteilung). Synthese des 5-Methyl-azulens. [On the knowledge of the sesquiterpenes. (53rd communication). Synthesis of 5-methyl-azulene.] Helvetica Chimica Acta, 25: 590-594. https://doi.org/10.1002/hlca.19420250317
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