Pfitzner-Moffatt oxidation

What is Pfitzner-Moffatt oxidation?

The Pfitzner-Moffatt oxidation, also referred to as the Moffatt oxidation, is a gentle oxidation process used to oxidize primary and secondary alcohols. This process is promoted by the activation of dimethyl sulfoxide (DMSO) with dicyclohexylcarbodiimide (DCC) and involves the use of alkoxysulfonium ylides that undergo intramolecular rearrangement to produce aldehydes and ketones, respectively (see list of acronyms).

Pfitzner-Moffatt oxidation
Pfitzner-Moffatt oxidation

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