Sarett oxidation

What is Sarett oxidation?

Sarett oxidation is the conversion of primary and secondary alcohols to aldehydes (and/or carboxylic acids) and ketones by means of CrO3-pyridine complex.

Sarett oxidation - CrO3-pyridine complex
Sarett oxidation


Approaches to the Total Synthesis of Adrenal Steroids.1 V. 4b-Methyl-7- ethylenedioxy-1,2,3,4,4aα,4b,5,6,7,8,10,10a β-dodecahydrophenanthrene-4 β-ol-1-one and Related Tricyclic Derivatives
G. I. Poos, G. E. Arth, R. E. Beyler, and L. H. Sarett
Journal of the American Chemical Society 1953 75 (2), 422-429
DOI: 10.1021/ja01098a049