Sonn-Müller method

What is Sonn-Müller method?

The Sonn-Müller method is a chemical process that is utilized to convert aromatic anilides into aldehydes. The reaction involves treating the anilide with phosphorus pentachloride, resulting in the formation of an imidoyl chloride, which is then reduced to the imine using a combination of stannous chloride and hydrochloric acid. The resulting imine is hydrolyzed, leading to the formation of the aldehyde.

Sonn-Müller method
Sonn-Müller method

References

  • Sonn, A. and Müller, E. (1919), Über eine neue Methode zur Umwandlung von Carbonsäuren in Aldehyde. [On a new method for the conversion of carboxylic acids to aldehydes.] Ber. dtsch. Chem. Ges. A/B, 52: 1927-1934. https://doi.org/10.1002/cber.19190521002
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