Tishchenko reaction

What is Tishchenko reaction?

The Tishchenko reaction, which is sometimes referred to as the Claisen-Tischischenko reaction, is a chemical process that involves the formation of esters from aldehydes via an oxidation-reduction mechanism. This reaction is typically carried out in the presence of aluminum or sodium alkoxides.

Tishchenko reaction - Claisen-Tischischenko reaction
Tishchenko reaction

References

  • Claisen, L. (1887), Ueber die Einwirkung von Natriumalkylaten auf Benzaldehyd. [On the effect of sodium alkylates on benzaldehyde.] Ber. Dtsch. Chem. Ges., 20: 646-650. https://doi.org/10.1002/cber.188702001148
  • V. Tishchenko, “On the effect of aluminium alkoxides on aldehydes. Ester condensation, as a new kind of aldehyde condensation” J. Russ. Phys. Chem. Soc. 38, 355-418 (1906)
  • V. Tishchenko, “On the effect of magnesium amalgam on isobutyric aldehyde” J. Russ. Phys. Chem. Soc. 38, 540-547 (1906)
  • V. Tishchenko, On the effect of magnesium amalgam on acetic aldehyde” J. Russ. Phys. Chem. Soc. 38, 547-550 (1906)
  • V. Tishchenko, Chem. Zentr. 1906 II, 1309
  • V. Tishchenko, Chem. Zentr. 1906 II, 1552
Shares