Trost allylation

What is Trost allylation?

The Trost allylation, also referred to as the Tsuji-Trost reaction, is a chemical process that involves the palladium-catalyzed allylation of nucleophiles. The reaction mechanism may proceed via an SN2 or SN2-like pathway, which is dependent on the specific catalyst used, the nucleophile involved, and the substituents on the substrate.

Trost allylation - Tsuji-Trost allylation - palladium-catalyzed
Trost allylation

NuH = malonate, β-diketone, β-ketoester, enamine and β-ketosulfone.

References

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