von Richter cinnoline synthesis

What is von Richter cinnoline synthesis?

The von Richter cinnoline synthesis involves the creation of cinnoline derivatives through a process that includes diazotization of o-aminoarylpropiolic acids or o-aminoarylacetylenes, along with subsequent hydration and cyclization.

von Richter cinnoline synthesis - general reaction scheme
von Richter cinnoline synthesis

References

v. Richter, V. (1883), Ueber Cinnolinderivate. [On cinnoline derivatives] Ber. Dtsch. Chem. Ges., 16: 677-683. https://doi.org/10.1002/cber.188301601154

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