What is Meerwein arylation?
The Meerwein arylation refers to the production of arylated olefins resulting from the treatment of olefins with diazonium salts while in the presence of cupric salts.
Z = C=C, C=O, Ar, CN, H
References
- Meerwein, H., Büchner, E. and van Emster, K. (1939), Über die Einwirkung aromatischer Diazoverbindungen auf α,β-ungesättigte Carbonylverbindungen. [On the effect of aromatic diazo compounds on α,β-unsaturated carbonyl compounds.] J. Prakt. Chem., 152: 237-266. https://doi.org/10.1002/prac.19391520705
- H. Meerwein, (1935) “Verfahren zur Einfuehrung von Arylgruppen in α,β-ungesaettigte Carbonylverbindungen und deren Derivate” [Process for the introduction of aryl groups into α,β-unsaturated carbonyl compounds and their derivatives] German Patent 714573C
Full Professor of Organic Chemistry at the University of Granada, with a long-standing research career in Computational Chemistry and molecular modeling and design.