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Transformations in Substituted Aromatic Compounds – problem list
Propose a method for the preparation of styrene (vinylbenzene) and acetophenone (phenylmethylketone) from ethyl benzene.
Describe the result of treating 3-methylphenol, with potassium dichromate in the presence of sulfuric acid.
Prepare the F, Cl, I and Br derivatives of benzene from aniline.
Design a synthetic route (A, B and C) for the preparation of 1-[(4-hydroxyphenyl)diazenyl]naphthalen-2-ol using naphthalen-2-ol.
From benzene, prepare diphenyl sulfide.
Synthesize from benzene the following derivatives:
Complete the following scheme:
Describe a method to perform the following transformations:
Propose a method of synthesis of the following compounds from benzene, assuming that in the case of formation of isomers, these can be separated.
Prepare the following halogenated derivatives from benzene.
Synthesize the following compounds starting from nitrobenzene, aniline or phenol, as appropriate.
Prepare the following compounds from toluene, using the organic and inorganic reagents that you consider necessary.
Describe the procedure for obtaining 4-bromo-1,2-dimethylbenzene and 1-bromo-2,3-dimethylbenzene from o-xylene.
p-Aminobenzoic acid is a component of some sunscreens. Devise some feasible procedure for the synthesis of said product from benzene.
Propose a method for the synthesis of 2-isopropylaniline from aniline.
Complete the following synthetic route:
Chlorpromazine is a drug used for the treatment of certain psychic disorders (schizophrenia, acute psychosis, delirium, etc.). Its synthesis can be performed according to the following scheme. Complete it (A, B and C) indicating, in the boxes the type of reaction used in each case.
Perform the following conversions:
Predict the structure of the products in the following sequence of reactions:
Complete the following reactions:
From benzene obtain the three nitrobenzoic acids (ortho-, meta– and para-).
Order by increasing acidity the following phenols:
From benzene obtain 3-chlorophenol.