Written by J.A Dobado | Last Updated on September 15, 2025
What is Meerwein arylation?
The Meerwein arylation refers to the production of arylated olefins resulting from the treatment of olefins with diazonium salts while in the presence of cupric salts.
Z = C=C, C=O, Ar, CN, H
References
- Meerwein, H., Büchner, E. and van Emster, K. (1939), Über die Einwirkung aromatischer Diazoverbindungen auf α,β-ungesättigte Carbonylverbindungen. [On the effect of aromatic diazo compounds on α,β-unsaturated carbonyl compounds.] J. Prakt. Chem., 152: 237-266. https://doi.org/10.1002/prac.19391520705
- H. Meerwein, (1935) “Verfahren zur Einfuehrung von Arylgruppen in α,β-ungesaettigte Carbonylverbindungen und deren Derivate” [Process for the introduction of aryl groups into α,β-unsaturated carbonyl compounds and their derivatives] German Patent 714573C
Full Professor of Organic Chemistry at the University of Granada, with a long-standing research career in Computational Chemistry and molecular modeling and design.