Bradsher cycloaddition

What is Bradsher cycloaddition?

The Bradsher cycloaddition involves a [4+2] cycloaddition reaction that occurs between a commonly used dienophile and cationic aromatic azadienes such as acridizinium or isoquinolinium.

Bradsher cycloaddition
Bradsher cycloaddition

References

C.K. Bradsher, T.W.G. Solomons, “Acridizinium Ion Chemistry. II. The Diels-Alder Reaction
Journal of the American Chemical Society 1958 80 (4), 933-934
DOI: 10.1021/ja01537a045

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