Written by J.A Dobado | Last Updated on September 15, 2025
What is Bucherer carbazole synthesis?
The Bucherer carbazole synthesis is a chemical reaction that involves the formation of carbazoles from naphthols or naphthylamines, aryl hydrazines, and sodium bisulfite, NaHSO3. The reaction produces the desired carbazole products.
References
Bucherer, H.T. and Seyde, F. (1908), Über die Einwirkung schwefligsaurer Salze auf aromatische Amino- und Hydroxylverbindungen. [On the effect of sulfurous acid salts on aromatic amino and hydroxyl compounds.] J. Prakt. Chem., 77: 403-413. https://doi.org/10.1002/prac.19080770133
Full Professor of Organic Chemistry at the University of Granada, with a long-standing research career in Computational Chemistry and molecular modeling and design.