What is Bucherer reaction?
Bucherer reaction , also known as Bucherer-Le Petit naphthol synthesis, or Bucherer-Le Petit naphthylamine synthesis, is the reversible formation of β-naphthylamine from β-naphthol and aqueous ammonium sulfite or bisulfite by means of intermediates formation of tetralonesulfonic and tetraloneiminosulfonic acids.
References
- R. Le Petit, Bulletin de la Société Industrielle de Mulhouse 73, 326 (1903).
- Bucherer, H.T. (1904), Über die Einwirkung schwefligsaurer Salze auf aromatische Amido- und Hydroxylverbindungen. [On the effect of sulfurous acid salts on aromatic amido and hydroxyl compounds.] J. Prakt. Chem., 69: 49-91. https://doi.org/10.1002/prac.19040690105
Full Professor of Organic Chemistry at the University of Granada, with a long-standing research career in Computational Chemistry and molecular modeling and design.