Fischer-Hepp rearrangement

What is Fischer-Hepp rearrangement?

The Fischer-Hepp rearrangement, which is also known as the nitrosamine rearrangement, is a chemical reaction that results in the rearrangement of secondary aromatic nitrosamines to form p-nitrosoarylamines.

Fischer-Hepp rearrangement - general reaction scheme - nitrosamine rearrangement
Fischer-Hepp rearrangement


Fischer, O. and Hepp, E. (1886), Zur Kenntniss der Nitrosamine. [On the knowledge of nitrosamines.] Ber. Dtsch. Chem. Ges., 19: 2991-2995.