What is Suárez reaction?
The Suárez reaction, also known as Suárez fragmentation or Suárez cleavage, involves the photoinduced conversion of hydroxyl-containing substrates with hypervalent iodine I(III) I2, resulting in the formation of the corresponding oxygen-centered radical (see list of acronyms).
References
- J.I. Concepción; C.G. Francisco; R. Hernández; J.A. Salazar; E. Suárez, “Intramolecular hydrogen abstraction. Iodosobenzene diacetate, an efficient and convenient reagent for alkoxy radical generation” Tetrahedron Lett. 25, 1953 (1984) DOI: 10.1016/S0040-4039(01)90085-1
- J.I. Concepción; C.G. Francisco; R. Freire; R. Hernández, J.A. Salazar; E. Suárez, “Iodosobenzene diacetate, an efficient reagent for the oxidative decarboxylation of carboxylic acids” The Journal of Organic Chemistry 51, 402-404 (1986) DOI: 10.1021/jo00353a026
Full Professor of Organic Chemistry at the University of Granada, with a long-standing research career in Computational Chemistry and molecular modeling and design.