Borsche-Drechsel cyclization

What is Borsche-Drechsel cyclization?

The Borsche-Drechsel cyclization is a chemical process that involves the transformation of cyclohexanone phenylhydrazone into tetrahydrocarbazole through an acid-catalyzed rearrangement.

Borsche–Drechsel cyclization - general reaction scheme
Borsche-Drechsel cyclization

This rearrangement is followed by an oxidation step, resulting in the formation of carbazole.

References

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