Gattermann-Koch formylation

What is Gattermann-Koch formylation?

Gattermann-Koch formylation is a process in which benzene, alkylbenzenes, or polycyclic aromatic hydrocarbons are formylated with carbon monoxide, CO, and hydrogen chloride, HCl, in the presence of aluminum chloride, AlCl3, under high pressure. The introduction of cuprous chloride, Cu2Cl2, enables the reaction to occur under atmospheric pressure.

Gattermann-Koch formylation
Gattermann-Koch formylation

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