Westphalen-Lettré rearrangement

What is Westphalen-Lettré rearrangement?

The Westphalen-Lettré rearrangement refers to a chemical reaction that involves the dehydration of derivatives of 5-hydroxycholesterol, along with the migration of the C-10 to C-5 methyl group in compounds containing a β-substituent at the C-6 position.

Westphalen-Lettré rearrangement - general reaction scheme
Westphalen-Lettré rearrangement

References

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