Reactions of Alcohols, Ethers and Oxiranes

The most significant reactions in organic chemistry of the functional groups alcohols, ethers and oxiranes are described below. Dehydration of alcohols Alcohols in the presence of mineral acids suh as H2SO4 o H3PO4 they give alkenes by loss of a water molecule. The order of reactivity of alcohol is: tertiary (3º) > secondary (2º) > … Read more

Reactions of Carboxylic Acids and Derivatives

Preparation of derivatives When the OH in a carboxylic acid is replaced by another function such as X (Cl, Br), OR, NH2, etc., compounds called “carboxylic acid derivatives” are obtained. All of them have in common the acyl group (R-C=O). These derivatives are, in turn, converted to acids by hydrolysis, and also give rise to … Read more

Synthesis and Reactivity of Organic Compounds

In order to understand all the aspects involved in the synthesis and reactivity of organic molecules, it is important to understand the main reactions of these functional groups in the simplest cases. Therefore, the study of monofunctional molecules (having only one main functional group) is addressed first. Here, you will find general characteristics, as well … Read more

Seven-membered heterocycles

What are 7-membered unsaturated heterocycles? The 7-membered unsaturated heterocycles with a nitrogen, oxygen and sulfur atom are systematically named azepines, oxepines and thiepines, respectively. fig-00 Only thiepines with bulky substituents are known but both oxepine and 1H-azepine have been synthesized. 1H-azepine and the oxepine are not flat and there is no evidence that they are … Read more

Four-membered heterocycles

What are 4-membered heterocycles ? Four-membered heterocycles show less ring strain than the 3-membered rings and therefore have fewer applications as synthetic intermediates. These heterocycles are less frequent due to the difficulty of preparing 4-membered rings. They exhibit different properties from the major and minor rings. fig-01 The three compounds in the figure (oxetane, azetidine … Read more

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